Thomas Duke
Cavendish Laboratory
Madingley Road
Cambridge CB3 0HE
email: td18@cam.ac.uk
tel: +44 1223 337256
fax: +44 1223 337356
Teaching
Miscellaneous
[1] T.A.J. Duke,
Tube model of field-inversion electrophoresis
Phys. Rev. Lett. 62, 2877-2880 (1989).
[2] T.A.J. Duke, G.C. Barker and A. Mehta,
Monte Carlo study of granular relaxation
Europhys. Lett. 13, 19-24 (1990).
[3] T.A.J. Duke,
Monte Carlo reptation model of gel electrophoresis: Steady state behavior
J. Chem. Phys. 93, 9049-9054 (1990).
[4] T.A.J. Duke,
Monte Carlo reptation model of gel electrophoresis: Response to field pulses
J. Chem. Phys. 93, 9055-9061 (1990).
[5] T.A.J. Duke & J.L. Viovy,
Simulation of megabase DNA undergoing gel electrophoresis
Phys. Rev. Lett. 68, 542-545 (1992).
[6] J.L. Viovy, T. Duke & F. Caron,
The physics of DNA electrophoresis
Contemp. Phys. 33, 1-40 (1992).
[7] T.A.J. Duke & J.L. Viovy,
Motion of megabase DNA during field-inversion gel electrophoresis: investigation by non-local Monte Carlo
J. Chem. Phys. 96, 8552-8563 (1992).
[8] T.A.J. Duke, A.N. Semenov & J.L. Viovy,
Mobility of a reptating polymer
Phys. Rev. Lett. 69, 3260-3263 (1992).
[9] T.A.J. Duke,
Molecular mechanisms of DNA electrophoresis
Intl. J. Genome Res. 1, 227-247 (1993).
[10] J.L. Viovy & T. Duke,
DNA electrophoresis in polymer solutions: Ogston sieving, reptation and constraint release
Electrophoresis 14, 322-329 (1993).
[11] T. Duke, J.L. Viovy & A.N. Semenov,
Electrophoretic mobility of DNA in gels I: New biased reptation theory including fluctuations
Biopolymers 34, 239-248 (1994).
[12] C. Heller, T. Duke & J.L. Viovy,
Electrophoretic mobility of DNA in gels II: Systematic experimental study in agarose gels
Biopolymers 34, 249-259 (1994).
[13] T. Duke and J.L. Viovy,
Theory of DNA electrophoresis in physical gels and polymer solutions
Phys. Rev. E 49, 2408-2415 (1994).
[14] W.D. Volkmuth, T. Duke, M.C. Wu, R.H. Austin & A. Szabo,
DNA electrodiffusion in a 2-D array of posts
Phys. Rev. Lett. 72, 2117-2120 (1994).
[15] J.L. Viovy & T. Duke,
Solid friction and polymer relaxation in gel electrophoresis
Science 264, 112-113 (1994).
[16] S.P. Obukhov, M. Rubinstein & T. Duke,
Diffusion of a ring polymer in a gel
Phys. Rev. Lett. 73, 1263-1266 (1994).
[17] T. Duke, T.E. Holy & S. Leibler,
"Gliding assays" for motor proteins: A theoretical analysis
Phys. Rev. Lett. 74, 330-333 (1995).
[18] A.N. Semenov, T.A.J. Duke & J.L. Viovy,
Gel electrophoresis of DNA in moderate fields: The effect of fluctuations
Phys. Rev. E 51, 1520-1537 (1995).
[19] M.S. Hutson, G. Holzwarth, T.A.J. Duke & J.L. Viovy,
Two-dimensional motion of DNA bands during 120û pulsed field gel electrophoresis I: Effect of molecular weight
Biopolymers 35, 297-306 (1995).
[20] L.M. Neitzey, G. Holzwarth, T.A.J. Duke & J.L. Viovy,
Two-dimensional motion of DNA bands during pulsed field gel electrophoresis II: Effect of field angle
Biopolymers 35, 307-317 (1995).
[21] L. Bourdieu, T. Duke, M. Elowitz, D.A. Winkelman, S. Leibler & A. Libchaber,
Spiral defects in motility assays: A measure of motor protein force
Phys. Rev. Lett. 75, 176-179 (1995).
[22] W.D. Volkmuth, T. Duke, R.H. Austin & E.C. Cox,
Trapping of branched DNA in microfabricated structures
Proc. Natl. Acad. Sci. USA 92, 6887-6892 (1995).
[23] T. Duke, R.H. Austin, E.C. Cox & S.S. Chan,
Pulsed-field electrophoresis in microlithographic arrays
Electrophoresis 17, 1075-1079 (1996).
[24] T. Duke & S. Leibler,
Motor protein mechanics: A stochastic model with minimal mechano-chemical coupling
Biophys. J. 71, 1235-1247 (1996).
[25] T. Duke, G. Monnelly, E.C. Cox & R.H. Austin,
Sequencing in nanostructures: A feasibility study
Electrophoresis 18, 17-22 (1997).
[26] R.H. Austin, J. Brody, E.C. Cox, T. Duke & W.D. Volkmuth,
Stretch genes
Physics Today 50.2, 32-38 (1997).
[27] T.A.J. Duke & R.H. Austin,
Microfabricated sieve for the continuous sorting of macromolecules
Phys. Rev. Lett. 80, 1552-1555 (1998).
[28] O.B. Bakajin, T.A.J. Duke, C.F. Chou, S.S. Chan, R.H. Austin & E.C. Cox,
Electrohydrodynamic stretching of DNA in confined environments
Phys. Rev. Lett. 80, 2737-2740 (1998).
[29] T. Duke,
Separation techniques
Current Opin. Chem. Biol. 2, 592-596 (1998).
[30] Y. Shi & T. Duke,
Cooperative model of bacterial sensing
Phys. Rev. E 58, 6399-6406 (1998).
[31] T.A.J. Duke,
Molecular model of muscle contraction
Proc. Natl. Acad. Sci. USA 96, 2770-2775 (1999).
[32] T.A.J. Duke & D. Bray,
Heightened sensitivity of a lattice of membrane receptors
Proc. Natl. Acad. Sci. USA 96, 10104-10108 (1999).
[33] C.F. Chou, O.B. Bakajin, S.W. Turner, T.A.J. Duke, S.S. Chan, E.C. Cox, H.G. Craighead & R.H. Austin,
Sorting by diffusion: an asymmetric obstacle course for continuous molecular separation
Proc. Natl. Acad. Sci. USA 96, 13762-13765 (1999).
[34] S. Camalet, T. Duke, F. Julicher & J. Prost,
Auditory sensitivity provided by self-tuned critical oscillations of hair cells
Proc. Natl. Acad. Sci. USA 97, 3183-3188 (2000).
[35] T.A.J. Duke,
Cooperativity of myosin molecules through strain-dependent chemistry
Phil. Trans. Roy. Soc. B 355, 529-538 (2000).
[36] C.F. Chou, R.H. Austin, O. Bakajin, J.O. Tegenfeldt, J.A. Castelino, S.S Chan, E.C. Cox, H. Craighead, N. Darnton, T. Duke, J.Y. Han & S. Turner,
Sorting biomolecules with microdevices
Electrophoresis 21, 81-90 (2000).
[37] J.O. Tegenfeld, O. Bakajin, C.F. Chou, S.S. Chan, R. Austin, W. Fann, L. Liou, E. Chan, T. Duke & E.C. Cox,
A near-field scanner for moving molecules
Phys. Rev. Lett. 86, 1378-1381 (2001).
[38] T.A.J. Duke, N. le Novere & D. Bray,
Conformational spread in a ring of proteins: a stochastic approach to allostery
J. Mol. Biol. 308, 541-553 (2001).
[39] F. Julicher, D. Andor & T. Duke,
The physical basis of two-tone interference in hearing
Proc. Natl. Acad. Sci. USA 98, 9080-9085 (2001).
[40] O. Bakajin, T.A.J. Duke, J.O. Tegenfeld, C.F. Chou, S.S. Chan, R.H. Austin & E.C. Cox,
Separation of 100 kilobase DNA molecules in 10 seconds
Anal. Chem. 73, 6053-6056 (2001).
[41] R.H. Austin, N. Darnton, R. Huang, O. Bakajin & T. Duke,
Ratchets: The problem with boundary conditions in conducting solutions
Applied Phys. A 75, 279-284 (2002).
[42] T. Duke,
The power of hearing
Physics World 15:5, 29-33 (2002).
[43] T. Duke,
Push or pull? Teams of motor proteins have it both ways
Proc. Natl. Acad. Sci. USA 99, 6521-6523 (2002).
Conference proceedings etc.
[1] T.A.J. Duke,
Monte Carlo modelling of gel electrophoresis
in 'Proceedings of the first international conference on electrophoresis, supercomputing and the human genome', eds. C.R. Cantor and H.A. Lim. (World Scientific 1991) pp. 75-85.
[2] T. Duke,
The physics of DNA electrophoresis
in 'Biologically inspired physics', ed. L. Peliti (Plenum 1991) pp. 71-80.
[3] T. Duke,
Computer simulation of DNA electrophoresis
Analusis 21, M29-31 (1993).
[4] T. Duke & R.H. Austin,
Microchips for sorting DNA
in 'Physics of biological systems', eds. H. Flyvbjerg et al. (Springer 1997) pp. 18- 25.
[5] O. Bakajin, T.A.J. Duke, C.F. Chou, J. Tegenfeldt, S.S. Chan, R.H. Austin & E.C. Cox,
Microfabricated arrays for fractionation of large DNA molecules via pulsed-field electrophoresis
in'Biological Physics: third international symposium', eds. H. Frauenfelder, G. Hummer and R. Garcia, pp. 243-248, AIP press (1999).
[6] T. Duke & F. Julicher,
Les proteines motrices: la main d'oeuvre de la cellule
Images de la Physique (2001).
[7] T. Duke,
Models of motor protein systems
Les Houches Lecture Notes (in press, 2002).
