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Acknowledgements

I would first like to acknowledge the funding from ML Laboratories plc without which I would not have the opportunity to undertake this research. I would also like to thank my supervisor Dr M.C. Payne for his guidance and Dr. R. N. Boyes for his help navigating the realms of pharmacology. Many members of TCM have provided support and many a stimulating debate, however I would like to thank Rajiv Shah in particular for his help and patience answering a myriad of technical questions.

Finally, and far from least, I would like to thank my parents and Imogen for their support without which this research would not have been possible.

I would like to acknowledge the use of the EPSRC funded Chemical Database Serivce at Daresbury.



Mr. Matthew D. Segall
Fri Jul 21 15:33:30 BST 1995