skip to primary navigation skip to content

Theory of Living Matter Group



In this tutorial, Gopi Shah (CRUK CI) and Vikas Trivedi (Department of Genetics)) will teach us about Light Sheet Microscopy .

Light sheet microscopy has emerged as the imaging tool of choice since its first successful demonstration for live imaging of biological specimen in 2004. At the core of this technique lies the orthogonality of illumination and detection axes, unlike the more conventional geometries, such as the ones in confocal or epi-illumination microscopes, where the two light paths are co-axial. The illumination is achieved through a sheet of light (instead of a beam as used in confocal) and the illuminated plane is imaged onto a camera, thereby giving this technique its commonly used name Selective Plane Illumination Microscopy (SPIM). Such an arrangement achieves high performance in imaging speed, multi-sided illumination and detection, high signal to background and diffraction-limited resolution, while inducing low photodamage, thereby allowing extended 4D imaging of biological processes. In this workshop we will provide a general overview of the technique, its historical development, current advancements- both commercial and custom-built, as well as the future and scope of this imaging technique as seen through the eyes of two long term users/developers of light-sheet microscope.

After the tutorial there will be plenty of time for informal discussions. We will serve some snacks and there will be opportunities to order food and drinks.

Date and venue

Date: Wednesday, 2rd November 2016 from 6pm

Venue: Panton Arms, 43 Panton St, CB2 1HL

The Panton Arms is roughly located between Tennis Court Road and the Botanic Garden.


No registration is necessary.

Do you think your experimental work might benefit from theoretical insights? Are you a theorist who would like to present his work to an interdisciplinary audience? Then why not give a talk in one of our meetings? Just send us an email at .