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Theory of Living Matter Group

TLM / NanoDTC meeting

Image courtesy of Floris Bosveld and Boris Guirao


This meeting will be jointly organised with NanoDTC and it will be focussed on the biophysics of subcellular structures and of cells contributing to morphogenesis. On this special occasion we have two external speakers who are renowned experts in studying the dynamics of the cytoskeleton and of developing tissues: Yohanns Bellaiche (Institut Curie, CNRS, Paris) will be talking about Cell division and epithelial tissue morphogenesis.

Questions related to embryo shape or morphogenesis have haunted developmental biologists for decades. Recent advances in imaging, cell biology, signal transduction and biophysics have framed the study of tissue morphogenesis in terms of collective cell dynamics and the interplay between biochemical and mechanical processes. Recent findings have confirmed that proliferative epithelial tissues reshape via morphogenetic processes such as cell shape change and cell rearrangements. Yet cell division remodels adherent junctions and modulates both tissue mechanics and tissue dynamics. Therefore its role and interplay with the other morphogenetic processes need to be understood to decipher the mechanisms of tissue morphogenesis. Moreover, given the large size of some proliferative tissues, challenging questions can be addressed: How do local and long-range mechanical effects contribute to tissue dynamics? How do the combinations of several signaling pathways or gene expression patterns specify distinct local cell dynamics leading to the emergence of several morphogenetic movements within a given tissue? During my talk I will describe some of our latest works that aim to understand the mechanisms of mitotic

Ewa Paluch (Laboratory of Molecular Cell Biology, UCL) will be talking about Actin Cortex mechanics in Cell Morphogenesis.

After the talk there will be plenty of time for informal discussions. We will serve some snacks and wine.

Date and venue

Date: Thursday, 4th June from 6pm-8:30pm

Venue: Main lecture theatre, Sainsbury Laboratory, Bateman St., Cambridge CB2 1NN

The Sainsbury Laboratory Cambridge University is located in Cambridge University Botanic Garden and can be accessed via Bateman Street. Note that the entrance to the Sainsbury Laboratory is rather hidden in the backyard of an arts school. There will be signs and people waiting to guide the way.


To judge attendance please briefly register here in case you plan to take part:
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